The Viscotek SEC-MALS 20 is a multi angle light scattering detector that can be used to measure the absolute molecular weight of molecules. It simultaneously measures the intensity of scattering at each angle which, in conjunction with a concentration detector, enables the calculation of the absolute molecular weight of proteins, synthetic & natural polymers and also molecular size expressed as the radius of gyration, Rg. For proteins, SEC-MALS measures the absolute molecular weight independent of column retention volume in order to study oligomeric state and aggregation.
